|
T9915 |
Eculizumab
|
|
Complement System
|
|
Eculizumab is a recombinant humanized monoclonal antibody against the complement protein C5 |
|
T9962 |
Mepolizumab
|
SB 240563 |
IL Receptor
|
|
Mepolizumab (SB 240563) is a humanized monoclonal antibody neutralizing IL-5. Mepolizumab can be used in studies about severe eosinophilic asthma and eosinophilic granulomatosis with polyangiitis. |
|
T9922 |
Matuzumab
|
|
EGFR
|
|
Matuzumab is a humanized monoclonal antibody used in cancer treatment. It has a high affinity for EGFR frequently associated with the growth of blood vessels in malignancy facilitating tumor growth and survival. |
|
T77480 |
Bivatuzumab
|
BIWA 4 |
Others
|
|
Bivatuzumab (BIWA 4) is a humanized monoclonal antibody against CD44v6. |
|
T77099 |
Nimacimab
|
JNJ 2463,RYI-018 |
Others
|
|
Nimacimab is a recombinant humanized monoclonal antibody. It can improve diabetes and non-alcoholic steatohepatitis. |
|
T77406 |
Lorvotuzumab
|
|
Others
|
|
Lorvotuzumab (Anti-NCAM1/CD56 Reference Antibody (lorvotuzumab)) is a humanized monoclonal antibody that binds to CD56 (NCAM1). Lorvotuzumab can be used to synthesize antibody-drug conjugate (Lorvotuzumab mertansine). |
|
T77399 |
Crizanlizumab
|
ADAKVEO,SEG-101 |
Others
|
|
Crizanlizumab (Adakveo) is a humanized monoclonal antibody against P-selectin for the prevention of pain crises in sickle cell disease. |
|
T76975 |
Tomaralimab
|
OPN-305 |
TLR
|
|
Tomaralimab (OPN-305) is a humanized IgG4 monoclonal antibody targeting TLR2. Tomarlimab is used to study myelodysplastic syndromes (MDS). |
|
T9904 |
Bevacizumab
|
|
VEGFR
|
|
Bevacizumab, a humanized monoclonal antibody, specifically and with high affinity binds to all isoforms of VEGF-A. |
|
T76888 |
Quetmolimab
|
E-6011,KANAb 001 |
Others
|
|
Quetmolimab is a humanized monoclonal antibody targeting chemokine ligand 1 (CX3CL1) that can be used to study rheumatoid arthritis. |
|
T77129 |
Belantamab
|
GSK2857914 |
TNF
|
|
Belantamab (GSK2857914) is a humanized IgG1 monoclonal antibody against BCMA (TNFRSF17). Belantamab is a naked antibody to Belantamab mafodotin and can be used to synthesize antibody-active molecule conjugates (Belantama... |
|
T77426 |
Pascolizumab
|
SB-240683 |
IL Receptor
|
|
Pascolizumab (SB-240683) is a humanized monoclonal antibody against IL-4. Pascolizumab has asthmatic effects and can be used to study allergic rhinitis. |
|
T76777 |
Bermekimab
|
MABp1 |
IL Receptor
|
|
Bermekimab (MABp1) is a humanized monoclonal antibody against interleukin-1α (IL-1α).Bermekimab has potential anti-inflammatory activity to prevent skin inflammation. |
|
T9926 |
Omalizumab
|
|
Others
|
|
Omalizumab is a recombinant humanized monoclonal antibody against human immunoglobulin E IgE) |
|
T9914 |
Vedolizumab
|
|
Integrin
|
|
Vedolizumab is a humanized monoclonal antibody that targets the α4β7 integrin for the treatment of Crohn's disease and ulcerative colitis. |
|
T76763 |
Teplizumab
|
PRV-031,MGA-031 |
Others
|
|
Teplizumab (MGA-031) is a humanized monoclonal antibody against CD3 that slows the loss of beta cell function.Teplizumab is used to treat type 1 diabetes. |
|
T35397 |
Sacituzumab
|
Sacituzumab,Sacituzumab (anti-Trop-2) |
|
|
Sacituzumab is a humanized IgG1 monoclonal antibody, a naked antibody to Sacituzumab govitecan be used to synthesize antibody-active small-molecule couplings.Sacituzumab has potential antitumor activity and is used in th... |
|
T9901A-006 |
Vonlerolizumab
|
Pogalizumab,RG 7888,MOXR 0916 |
Others
|
|
Vonlerolizumab(MOXR 0916) is a humanized IgG agonistic OX40-specific monoclonal antibody with potential antitumor activity for the study of tumors and immune diseases. |
|
T77135 |
Tafasitamab
|
MOR00208,XmAb5574,Tafasitamab-cxix |
Apoptosis
,
Immunology/Inflammation related
|
|
Tafasitamab (XmAb5574) is an FC-modified humanized monoclonal antibody targeting the human B-cell surface antigen CD19 for the study of diffuse large B-cell lymphoma. |
|
T9901A-002 |
Enoblituzumab
|
MGA271,TJ-271 |
Others
|
|
Enoblituzumab is a humanized IgG1 κmab monoclonal antibody that recognizes human B7-H3 protein and can be used to study solid tumors such as non-small cell lung cancer (NSCLC). |
|
T76673 |
Bemarituzumab
|
FPA144 |
FGFR
|
|
Bemarituzumab is a novel humanized IgG1 monoclonal antibody targeting FGFR2b. Bemarituzumab prevents FGFR2b from binding to FGF and activation. Potential applications of Bemarituzumab in cancer research. |
|
T76671 |
Amatuximab
|
MORab-009 |
Others
|
|
Amatuximab (MORab-009) is a chimeric IgG1/k monoclonal antibody humanized against cell surface mesoleptin (MSLN) with antitumor activity for the treatment of solid tumors. |
|
T76717 |
Serplulimab
|
HLX 10 |
COX
|
|
Serplulimab (HLX 10) is a humanized monoclonal anti-antibody to PD-1. Serplulimab has antitumor activity and can be used in small cell lung cancer and esophageal squamous cell carcinoma. |
|
T77448 |
Naxitamab
|
Naxitamab-gqgk,Humanized 3F8,Hu3F8 |
Others
|
|
Naxitamab (Hu3F8) is a humanized monoclonal antibody against GD2 (hu3F8). Naxitamab has antitumor activity and can be used to study neuroblastoma, osteosarcoma, and other GD2-positive cancers. |
|
T77750 |
Rosmantuzumab
|
OMP-131R10 |
Others
|
|
Rosmantuzumab (OMP-131R10) is a humanized monoclonal antibody against R-spondin 3 (RSPO3). Rosmantuzumab has potential antitumor activity and can be used to study advanced relapsed refractory solid tumors. |
|
T77369 |
Telazorlimab
|
ISB-830,GBR-830 |
Immunology/Inflammation related
|
|
Telazorlimab (GBR-830) is a humanized monoclonal antibody that targets the OX40 co-stimulatory receptor on activated T cells. Telazorlimab can be used to treat lupus erythematosus and atopic dermatitis. |
|
T9902 |
Atezolizumab
|
|
Apoptosis
,
PD-1/PD-L1
,
Autophagy
|
|
Atezolizumab anti-PD-L1) is a fully humanized IgG1 monoclonal antibody that blocks the interaction of PD-L1 with both PD-1 and B7.1 but not the interaction of PD-L2 with PD-1. |
|
T76792 |
Sibrotuzumab
|
BIBH 1,Anti-Human FAP Recombinant Antibody |
Others
|
|
Sibrotuzumab (BIBH 1) is a humanized IgG1 monoclonal antibody targeting Fibroblast Activating Protein (FAP).Sibrotuzumab is used in the study of colorectal cancer and non-small cell lung cancer. |
|
T9909 |
Pertuzumab
|
|
EGFR
|
|
Pertuzumab (anti-HER2) a humanized monoclonal antibody and the first in the class of agents called the HER2 dimerization inhibitors impairs the ability of HER2 to bind to other members of the HER family. |
|
T9912 |
Trastuzumab
|
|
EGFR
|
|
Trastuzumab is a humanized monoclonal antibody for patients with invasive breast cancers that overexpress HER2. Trastuzumab has been clinically used to treat HER2 Positive Metastatic Breast Cancer and HER2 Positive Gastr... |
|
T77364 |
Sibeprenlimab
|
VIS649,VIS-649 |
Others
|
|
Sibeprenlimab (VIS649) is a humanized IgG 2 monoclonal antibody that suppresses APRIL. Sibeprenlimab has an inhibitory effect on APRIL and may be studied for the prevention and treatment of kidney disease (IgAN). |
|
T9901A-004 |
Labetuzumab
|
IMMU-14,hMN-14,IMMU-100 |
|
|
Labetuzumab is a humanized anti-carcinoembryonic antigen (CEA) monoclonal antibody with anticancer activity that inhibits tumor growth and is used in the study of thyroid and colorectal cancer (CRC). |
|
T77359 |
Tezepelumab
|
Tezepelumab-ekko,MEDI 19929,AMG 157 |
Others
|
|
Tezepelumab (AMG 157) is a humanized monoclonal antibody (IgG2λ) targeting TSLP that prevents TSLP from interacting with its heterodimer receptor. Tezepelumab can be used to study advanced asthma disease. |
|
T76866 |
Icrucumab
|
LY 3012212,IMC-18F1 |
VEGFR
|
|
Icrucumab ( IMC-18F1) is a humanized IgG1 monoclonal antibody targeting vascular endothelial growth factor receptor-1.Icrucumab has antitumor activity.Icrucumab has been studied in metastatic colon cancer. |
|
T77415 |
Ladiratuzumab
|
hLIV22 |
Others
|
|
LadiratuzumAb (hLIV22) is a humanized monoclonal antibody targeting LIV-1/ZIP6.LadiratuzumAb is a naked antibody to SGN-LIV1A and is capable of synthesizing an antibody-activated molecule coupling (ADC), SGN-LIV1A.Ladira... |
|
T76698 |
Rovalpituzumab
|
|
Gamma-secretase
|
|
Rovalpituzumab is a humanized monoclonal antibody targeting delta-like protein 3 (DLL3). Rovalpituzumab can be used to synthesize antibody-active molecule conjugates (ADCs). Rovalpituzumab has anticancer activity and is ... |
|
T9911 |
Tocilizumab
|
|
Interleukin
|
|
Tocilizumab (anti-IL-6R) is a humanized monoclonal antibody that binds to the interleukin-6 receptor |
|
T77011 |
Flanvotumab
|
20D7S,IMC 20D7S |
Tyrosinase
|
|
Flanvotumab (IMC-20D7S) is a humanized monoclonal antibody directed against tyrosinase-related protein (TYRP1).Flanvotumab exhibits potent antitumor activity and acts through natural killer-mediated and antibody-dependen... |
|
T39057 |
Rozanolixizumab
|
UCB7665 |
Others
|
|
Rozanolixizumab (RYSTIGGO) is a high-affinity humanized immunoglobulin G4 monoclonal antibody targeting Fc receptors (FcRn) in human newborns for the study of pathogenic IgG in autoimmune and alloimmune diseases. |
|
T76784 |
Tildrakizumab
|
MK 3222,SCH 900222 |
IL Receptor
|
|
Tildrakizumab (SCH 900222) is a potent humanized monoclonal antibody against IL-23 (p19 subunit). Tildrakizumab targets single-stranded IL-23 with a Kd value of 136 pM. Tildrakizumab can be used to study psoriasis and ps... |
|
T76682 |
Galcanezumab
|
LY 2951742 |
CGRP Receptor
|
|
Galcanezumab is a humanized IgG4 monoclonal antibody targeting the CGRP ligand, which binds to the ligand calcitonin gene-related peptide. Galcanezumab can be used to prevent and treat migraines or cluster headaches. |
|
T9919 |
Alemtuzumab
|
|
Others
|
|
Alemtuzumab is a humanized monoclonal antibody against CD52 an antigen found on the surface of normal and malignant lymphocytes. |
|
T9901A-003 |
Gemtuzumab
|
CDP-771,CMA-676 |
|
|
Gemtuzumab(CMA-676) is a monoclonal antibody directed against the CD33 antigen and consists of a recombinant humanized IgG4 antibody.Gemtuzumab can be used to synthesize Gemtuzumab ozogamicin, an antibody coupled compoun... |
|
T77404 |
Tesnatilimab
|
IPH-23XX,JNJ-64304500,JNJ 4500 |
Others
|
|
Tesnatilimab is a potent humanized IgG4 monoclonal antibody that binds to the immune-activating receptor NKG2D. Tesnatilimab has potential immunomodulatory and anti-inflammatory activity and can be used to study active u... |
|
T9930 |
Secukinumab
|
|
IL Receptor
|
|
Secukinumab is a fully humanized monoclonal anti-IL-17A antibody and the first in its class to be approved by the US Food and Drug Administration for the treatment of moderate to severe plaque psoriasis. |
|
T77392 |
Pepinemab
|
VX 15/2503 |
Others
|
|
Pepinemab(VX 15/2503) is a humanized IgG4 monoclonal antibody targeting sematone 4D. Pepinemab has anti-cancer activity and blocks the activity of SEMA4D, which is used to study degenerative diseases similar to Alzheimer... |
|
T76828 |
Sonepcizumab
|
LT 1009 |
LPL Receptor
|
|
Sonepcizumab (LT 1009) is a fully humanized monoclonal antibody against S1P. Sonepcizumab has anti-cancer activity and can be used to study metastatic renal cell carcinoma (mRCC) to prevent eye scarring after glaucoma fi... |
|
T9908 |
Pembrolizumab
|
|
PD-1/PD-L1
|
|
Pembrolizumab is a humanized monoclonal antibody inhibiting the PD-1 receptor and the first in the class of agents called the HER2 dimerization inhibitors that impairs the ability of HER2 to bind to other members of the ... |
|
T77478 |
Milatuzumab
|
hLL1,MEDI-115 |
Others
|
|
Milatuzumab (MEDI-115) is a humanized monoclonal antibody against CD74. Milatuzumab promotes the production of free radical oxygen and the loss of mitochondrial membrane potential, reduces CD20/CD74 aggregates and cell a... |
|
T76907 |
Palivizumab
|
Synagis,MEDI 493 |
RSV
|
|
Palivizumab (MEDI 493) is a humanized RSV-specific monoclonal antibody that selectively inhibits epitopes at the F protein A antigenic site of RSV subtypes A and B for the prevention of respiratory syncytial virus infect... |
